Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 3/20 | 0.55 |
| ▸ | TBK1 | Q9UHD2 | 13/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15584270 | 0.93 | FLT3 (0.55) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15584276 | 0.93 | FLT3 (0.55) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15584121 | 0.91 | FLT3 (0.58) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL16444253 | 0.91 | FLT3 (0.58) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15584266 | 0.90 | FLT3 (0.53) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15584737 | 0.90 | FLT3 (0.56) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15584262 | 0.88 | FLT3 (0.55) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL16444323 | 0.85 | FLT3 (0.66) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15585831 | 0.85 | FLT3 (0.52) | FLT3TBK1PDPK1SIRT5 | |
| SCHEMBL15585820 | 0.84 | FLT3 (0.51) | FLT3TBK1PDPK1SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9145415-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2015-09-29 | — | — | US | disclosed |
| US-9145415-B2 | Nitrogen-containing heterocyclic compound or salt thereof | FUJIFILM CORPORATION (JP) | 2015-09-29 | — | — | US | disclosed |
| US-20150045339-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
| US-20150045339-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FUJIFILM CORPORATION (JP) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045339-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND OR SALT THEREOF | FLT3, NPM1, ABL1 | FLT3 1/4885TBK1 711/4885PDPK1 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.