Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2324973 | 0.84 | TSHR (0.44) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL2120183 | 0.79 | TSHR (0.40) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL15538517 | 0.78 | TSHR (0.42) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL15230588 | 0.78 | TSHR (0.39) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL21983652 | 0.77 | TSHR (0.43) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL13239550 | 0.75 | CYP1A2 (0.32) | CYP1A2CYP2C19 | |
| Diethylamine SCHEMBL16774724 | 0.75 | TSHR (0.41) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL11331956 | 0.74 | TSHR (0.47) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL11333895 | 0.74 | TSHR (0.47) | TSHRKDM4ETDP1CYP1A2CYP2C19 | |
| SCHEMBL11330708 | 0.74 | TSHR (0.47) | TSHRKDM4ETDP1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9056881-B2 | Process for the preparation of phosphinic acid esters | MERCK PATENT GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20150045572-A1 | PROCESS FOR THE PREPARATION OF PHOSPHINIC ACID ESTERS | MERCK PATENT GMBH (DE) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045572-A1 | PROCESS FOR THE PREPARATION OF PHOSPHINIC ACID ESTERS | PHOSPHO1, ALK, PTEN | TSHR 471/4885KDM4E 1568/4885TDP1 2656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.