Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | RAD52 | P43351 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12201165 | 0.98 | KDM4E (0.58) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL26662987 | 0.98 | KDM4E (0.58) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12201171 | 0.98 | KDM4E (0.58) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| Bromide SCHEMBL10439579 | 0.97 | KDM4E (0.61) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| Iodide SCHEMBL9292447 | 0.97 | KDM4E (0.61) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL12201138 | 0.95 | KDM4E (0.59) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL13645489 | 0.93 | KDM4E (0.64) | KDM4EHTTSMN1; SMN2POLBRECQL | |
| SCHEMBL13686278 | 0.91 | KDM4E (0.62) | KDM4EPOLBRECQLBCHEACHE | |
| SCHEMBL12201164 | 0.88 | KDM4E (0.62) | KDM4EHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL11579424 | 0.83 | KDM4E (0.51) | KDM4EHTTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150044143-A1 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | PHANOS TECHNOLOGIES, INC. (US) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150044143-A1 | FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE | TIMM44, SLC47A2, TIMM50 | KDM4E 4493/4885HTT 4328/4885SMN1; SMN2 4592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.