SCHEMBL16450528

SCHEMBL16450528

OCCOCCOOCCOCCOCCOCCOCCn1cc(CO)nn1

nearest known ligand 0.41

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.41
MAPT P10636 1/20 0.40
MAPK14 Q16539 4/20 0.39
LGALS3 P17931 1/20 0.39
NCF1 P14598 9/20 0.39
CYBB P04839 1/20 0.38
NOX5 Q96PH1 1/20 0.38
DRD2 P14416 2/20 0.38
DRD4 P21917 2/20 0.38
DRD3 P35462 2/20 0.38
DPP4 P27487 1/20 0.38
P2RX7 Q99572 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29329316 0.89 NOTUM (0.49) NOTUMMAPTLGALS3NCF1CYBB
SCHEMBL19576221 0.83 NOTUM (0.42) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL21643807 0.83 DPP4 (0.44) NOTUMMAPK14LGALS3NCF1CYBB
SCHEMBL19576220 0.83 NOTUM (0.42) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL19576085 0.83 NOTUM (0.42) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL19576157 0.83 GBA1 (0.49) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL19576084 0.83 GBA1 (0.49) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL19576228 0.83 NOTUM (0.42) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL19576173 0.83 GBA1 (0.49) NOTUMLGALS3NCF1CYBBNOX5
SCHEMBL14020289 0.81 MAPT (0.44) MAPTMAPK14LGALS3NCF1CYBB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015021079-A1 PROTECTED FLUORESCENT REAGENT COMPOUNDS PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) 2015-02-12 WO disclosed