Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRN | P28799 | 1/20 | 0.32 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16450873 | 1.00 | MAPK1 (0.44) | MAPK1GRNSORT1HRH2HRH1 | |
| SCHEMBL30173349 | 0.82 | MAPK1 (0.44) | MAPK1GRNSORT1HRH2HRH1 | |
| SCHEMBL561163 | 0.82 | MAPK1 (0.44) | MAPK1GRNSORT1SLC7A5NOS3 | |
| SCHEMBL1414721 | 0.82 | MAPK1 (0.44) | MAPK1GRNSORT1HRH2HRH1 | |
| SCHEMBL1576869 | 0.82 | MAPK1 (0.44) | MAPK1GRNSORT1HRH2HRH1 | |
| SCHEMBL1644294 | 0.82 | MAPK1 (0.44) | MAPK1GRNSORT1SLC7A5NOS3 | |
| SCHEMBL241174 | 0.82 | MAPK1 (0.44) | MAPK1GRNSORT1SLC7A5NOS3 | |
| Hydrochloric Acid SCHEMBL919391 | 0.80 | MAPK1 (0.43) | MAPK1GRNSORT1SLC7A5NOS3 | |
| SCHEMBL30589488 | 0.80 | MAPK1 (0.43) | MAPK1GRNSORT1SLC7A5NOS3 | |
| Hydrochloric Acid SCHEMBL920374 | 0.80 | MAPK1 (0.43) | MAPK1GRNSORT1SLC7A5NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9447136-B2 | Semisynthetic derivatives of Nystatin A1 | BLIRT S.A. (PL) | 2016-09-20 | — | — | US | disclosed |
| US-20150045316-A1 | SEMISYNTHETIC DERIVATIVES OF NYSTATIN A1 | BLIRT S.A. (PL) | 2015-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045316-A1 | SEMISYNTHETIC DERIVATIVES OF NYSTATIN A1 | NPC1, NPC1L1, LSS | MAPK1 1925/4885GRN 769/4885SORT1 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.