Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20454534 | 0.91 | CFTR (0.76) | CFTR | |
| SCHEMBL16445262 | 0.89 | CFTR (0.72) | CFTR | |
| SCHEMBL16451417 | 0.87 | CFTR (0.80) | CFTR | |
| SCHEMBL16445078 | 0.86 | CFTR (1.00) | CFTR | |
| SCHEMBL19879828 | 0.86 | CFTR (0.74) | CFTR | |
| SCHEMBL16444981 | 0.84 | CFTR (1.00) | CFTR | |
| SCHEMBL17467879 | 0.83 | CFTR (0.71) | CFTR | |
| SCHEMBL16445145 | 0.83 | CFTR (0.74) | CFTR | |
| SCHEMBL19879853 | 0.83 | CFTR (0.74) | CFTR | |
| SCHEMBL16445843 | 0.83 | CFTR (0.73) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015018823-A1 | THIENO[2,3-C]PYRANS AS CFTR MODULATORS | GALAPAGOS NV (BE) | 2015-02-12 | — | — | WO | disclosed |