Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445497 | 0.89 | CFTR (0.60) | CFTR | |
| SCHEMBL16446010 | 0.88 | CFTR (0.58) | CFTR | |
| SCHEMBL16445597 | 0.87 | CFTR (0.67) | CFTR | |
| SCHEMBL20496295 | 0.87 | CFTR (0.66) | CFTR | |
| SCHEMBL16445356 | 0.85 | CFTR (0.64) | CFTR | |
| SCHEMBL16445648 | 0.79 | CFTR (0.73) | CFTR | |
| SCHEMBL16445388 | 0.79 | CFTR (0.68) | CFTR | |
| SCHEMBL16444982 | 0.78 | CFTR (1.00) | CFTR | |
| SCHEMBL18196096 | 0.78 | CFTR (0.71) | CFTR | |
| SCHEMBL16445859 | 0.77 | CFTR (0.65) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015018823-A1 | THIENO[2,3-C]PYRANS AS CFTR MODULATORS | GALAPAGOS NV (BE) | 2015-02-12 | — | — | WO | disclosed |