Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | BRAF | P15056 | 2/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 8/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1646207 | 0.87 | MAPK14 (0.46) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1646248 | 0.82 | MAPK14 (0.58) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1645760 | 0.82 | MAPK14 (0.60) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1647484 | 0.81 | MAPK14 (0.65) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1646161 | 0.80 | MAPK14 (0.50) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1646093 | 0.79 | CSNK1D (0.53) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1644870 | 0.78 | MAPK14 (0.65) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1646943 | 0.75 | MAPK14 (0.54) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1647991 | 0.75 | MAPK13 (0.52) | MAPK13MAPK12MAPK11MAPK14CSNK1D | |
| SCHEMBL1646564 | 0.74 | MAPK13 (0.53) | MAPK13MAPK12MAPK11MAPK14CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |