SCHEMBL16452385

SCHEMBL16452385

COC(=O)c1nc[nH]c1COC=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.38
HSD17B10 Q99714 1/20 0.38
KDM4E B2RXH2 3/20 0.37
NPSR1 Q6W5P4 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
LMNA P02545 2/20 0.35
ALDH1A1 P00352 4/20 0.33
HPGD P15428 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
MAPK1 P28482 1/20 0.33
ATM Q13315 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23213731 0.79 KDM4E (0.45) CYP2C19HSD17B10KDM4ENPSR1SMN1; SMN2
SCHEMBL4962128 0.79 CYP2C19 (0.43) CYP2C19HSD17B10KDM4ENPSR1SMN1; SMN2
SCHEMBL12425701 0.76 CYP2C19 (0.49) CYP2C19HSD17B10KDM4ENPSR1SMN1; SMN2
SCHEMBL28318248 0.74 CYP2C19 (0.32) CYP2C19HSD17B10
SCHEMBL6895392 0.74 CYP2C19 (0.39) CYP2C19HSD17B10KDM4ENPSR1SMN1; SMN2
SCHEMBL4510342 0.72 NPSR1 (0.42) KDM4ENPSR1SMN1; SMN2LMNAALDH1A1
SCHEMBL27807509 0.70 PRKACA (0.32) CYP2C19HSD17B10
SCHEMBL27785682 0.70 CYP2C19 (0.30) CYP2C19HSD17B10
SCHEMBL2146034 0.70 NPSR1 (0.46) KDM4ENPSR1SMN1; SMN2LMNAALDH1A1
SCHEMBL5433655 0.70 NPSR1 (0.46) HSD17B10KDM4ENPSR1SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150044557-A1 NEGATIVE ELECTRODE ACTIVE MATERIAL FOR SODIUM-ION BATTERY, AND SODIUM-ION BATTERY TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2015-02-12 US disclosed