SCHEMBL1645310

SCHEMBL1645310

Cn1/c(=N\N)sc2ccccc21

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.64
GAA P10253 2/20 0.64
ALDH1A1 P00352 7/20 0.57
KMT2A Q03164 7/20 0.57
MEN1 O00255 4/20 0.57
ATM Q13315 1/20 0.57
NPC1 O15118 11/20 0.54
RAB9A P51151 11/20 0.54
SMN1; SMN2 Q16637 9/20 0.54
NPSR1 Q6W5P4 4/20 0.54
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2C19 P33261 1/20 0.54
NSD2 O96028 1/20 0.54
MCL1 Q07820 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
F12 P00748 1/20 0.53
KDM4E B2RXH2 3/20 0.49
NFKB1 P19838 2/20 0.49
NFKB2 Q00653 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566154 1.00 MAPT (0.64) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL29427484 1.00 MAPT (0.64) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL3966960 1.00 MAPT (0.64) MAPTGAAALDH1A1KMT2AMEN1
SCHEMBL29365359 1.00 MAPT (0.64) MAPTGAAALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL30738267 0.98 MAPT (0.62) MAPTGAAALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL691148 0.98 MAPT (0.62) MAPTGAAALDH1A1KMT2AMEN1
Water SCHEMBL11378791 0.98 MAPT (0.62) MAPTGAAALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL691147 0.98 MAPT (0.62) MAPTGAAALDH1A1KMT2AMEN1
Hydrochloric Acid SCHEMBL30073092 0.98 MAPT (0.62) MAPTGAAALDH1A1KMT2AMEN1
Water SCHEMBL11378787 0.98 MAPT (0.62) MAPTGAAALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 236 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2811031-B1 COMPOSITION FROM LOBSTER HEMOCYTE EXTRACT FOR DETECTION OF LIPOPOLYSACCHARIDES, PEPTIDOGLYCANS AND 1,3-BETA-D-GLUCANS. CENTRO DE INVESTIG Y DESARROLLO DE MEDICAMENTOS CIDEM (US) 2018-07-11 EP claimed
EP-2319937-B1 BLOOD COMPONENT MEASUREMENT METHOD UTILIZING HEMOLYZED WHOLE BLOOD, AND KIT FOR THE METHOD NIPPON KAYAKU KK (JP) 2016-01-27 EP claimed
EP-2533053-B1 Method for the determination of the concentration of vitamin B6 in a sample BÜHLMANN LAB AG (CH) 2015-09-09 EP claimed
EP-2071331-B1 Biosensors with porous chromatographic membranes I SENS INC (KR) 2013-10-16 EP claimed
EP-1763398-B1 SUPPORT-COLOURING MEANS DOUBLET LUC (BE) 2012-11-14 EP claimed
EP-1182456-B1 Biosensors with porous chromatographic membranes I SENS INC (KR) 2009-11-11 EP claimed
EP-1432981-B1 METHOD AND APPARATUS FOR TESTING ALDEHYDE IN A POLYESTER POLYMER HUSKY INJECTION MOLDING (CA) 2007-03-14 EP claimed
EP-1486778-B1 Electrochemical biosensor I SENS INC (KR) 2006-11-22 EP claimed
EP-1217373-B1 Hydrogen peroxide indicator employing enzyme and dye ETHICON INC (US) 2004-12-01 EP claimed
US-20020182600-A1 Method for assaying biological and other constituents using synthetic nucleounits in lateral flow, liquid, and dry chemistry techniques SMITH JACK V (US) 2002-12-05 US claimed
EP-0255708-A2 Indicator composition and method for the preparation thereof MILES INC. (US) 1988-02-10 EP claimed
WO-1987006619-A1 PROCESS AND REAGENT FOR DETECTING HEART LESIONS OR DISEASES BOEHRINGER MANNHEIM GMBH (DE) 1987-11-05 WO claimed
EP-0243901-A1 Process and reagent for the detection of heart lesions or heart diseases Roche Diagnostics GmbH (DE) 1987-11-04 EP claimed
EP-0125513-B1 PROCESS AND REAGENT FOR THE DETERMINATION OF THE HEMOGLOBIN-HAPTOGBIN COMPLEX IN THE PRESENCE OF FREE HEMOGLOBIN Roche Diagnostics GmbH (DE) 1987-09-09 EP claimed
US-4550076-A Rapid assaying method for guanase MARUHO CO., LTD. (JP) 1985-10-29 US claimed
EP-0148275-A1 PROCESS FOR DECOMPOSING ASCORBIC ACID WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1985-07-17 EP claimed
EP-0016578-B1 METHOD AND KIT FOR THE DETERMINATION OF BIOCIDE CONCENTRATION IN AQUEOUS SYSTEMS The British Petroleum Company p.l.c. (GB) 1985-01-02 EP claimed
US-4396714-A INDOPHENOL DYES DOJINDO LABORATORIES (JP) 1983-08-02 US claimed
EP-0075894-A1 A rapid assaying method for guanase MARUHO CO., LTD. (JP) 1983-04-06 EP claimed
EP-0007787-B1 METHOD AND REAGENT FOR THE QUANTITATIVE DETERMINATION OF HYDROGEN PEROXIDE KYOWA HAKKO KOGYO CO., LTD (JP) 1982-11-03 EP claimed