Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164541 | 1.00 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL174523 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635798 | 0.84 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL163139 | 0.84 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL12503625 | 0.83 | NAMPT (0.75) | NAMPTCYP2C9 | |
| SCHEMBL163455 | 0.83 | NAMPT (0.75) | NAMPTCYP2C9 | |
| SCHEMBL163456 | 0.83 | NAMPT (0.75) | NAMPTCYP2C9 | |
| SCHEMBL29635819 | 0.83 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL167267 | 0.83 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635783 | 0.82 | NAMPT (1.00) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611777-A1 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL]AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | Forma TM, LLC. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012031196-A9 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL] AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | FORMA TM, LLC (US) | 2013-06-13 | — | — | WO | disclosed |
| WO-2012031196-A1 | 4- { [ ( PYRIDIN- 3 - YL -METHYL) AMINOCARBONYL] AMINO} BENZENE - SULFONE DERIVATIVES AS NAMPT INHIBITORS FOR THERAPY OF DISEASES SUCH AS CANCER | FORMA THERAPEUTICS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |