Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16454451 | 1.00 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2593914 | 1.00 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2596195 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL16454441 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL16454488 | 0.89 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2590742 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL16454455 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL16454484 | 0.83 | PDE10A (1.00) | PDE10A | |
| SCHEMBL2590564 | 0.82 | PDE10A (1.00) | PDE10A | |
| SCHEMBL7702302 | 0.82 | PDE10A (1.00) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8957073-B2 | Unsaturated nitrogen heterocyclic compounds useful as PDE10 inhibitors | AMGEN INC. | 2015-02-17 | — | — | US | claimed |