Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 15/20 | 0.84 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.59 |
| ▸ | SRC | P12931 | 2/20 | 0.59 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.59 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.59 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | CSF1R | P07333 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14875643 | 0.93 | WEE1 (0.83) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL31557302 | 0.93 | WEE1 (0.83) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL16454981 | 0.91 | WEE1 (0.70) | WEE1 | |
| SCHEMBL31557251 | 0.91 | WEE1 (1.00) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL14875697 | 0.91 | WEE1 (1.00) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL31557174 | 0.87 | WEE1 (0.89) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL14875763 | 0.87 | WEE1 (0.89) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL16454976 | 0.87 | WEE1 (0.79) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL16454975 | 0.87 | WEE1 (0.76) | WEE1FGFR4SRCFGFR1FGFR2 | |
| SCHEMBL16445761 | 0.86 | WEE1 (0.73) | WEE1FGFR4SRCFGFR1FGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015019037-A1 | PHARMACEUTICAL COMPOUNDS | ALMAC DISCOVERY LIMITED (GB) | 2015-02-12 | — | — | WO | disclosed |