Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645651 | 1.00 | BACE1 (0.80) | BACE1MAPT | |
| SCHEMBL1646884 | 0.89 | BACE1 (1.00) | BACE1MAPT | |
| SCHEMBL1646886 | 0.89 | BACE1 (1.00) | BACE1MAPT | |
| SCHEMBL1646226 | 0.87 | BACE1 (0.82) | BACE1MAPT | |
| SCHEMBL1646231 | 0.87 | BACE1 (0.82) | BACE1MAPT | |
| SCHEMBL1648440 | 0.84 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1648443 | 0.84 | BACE1 (1.00) | BACE1 | |
| SCHEMBL1647362 | 0.84 | BACE1 (0.71) | BACE1 | |
| SCHEMBL1647359 | 0.84 | BACE1 (0.71) | BACE1 | |
| SCHEMBL1647006 | 0.83 | BACE1 (1.00) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552220-B2 | Therapeutic agent for Alzheimer's disease | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2013-10-08 | — | — | US | disclosed |
| EP-2305629-A1 | THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE | Tokyo Institute of Technology (JP) | 2011-04-06 | — | — | EP | disclosed |