Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.70 |
| ▸ | FABP1 | P07148 | 6/20 | 0.61 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.58 |
| ▸ | FABP4 | P15090 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16456677 | 0.91 | NR1H4 (0.69) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL2084630 | 0.90 | NR1H4 (0.70) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL16456780 | 0.88 | NR1H4 (0.61) | NR1H4 | |
| SCHEMBL16456775 | 0.87 | NR1H4 (0.67) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL2084229 | 0.85 | NR1H4 (0.71) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL16456714 | 0.84 | NR1H4 (0.64) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL2084137 | 0.83 | NR1H4 (0.68) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL29143461 | 0.82 | NR1H4 (1.00) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL2084048 | 0.82 | NR1H4 (0.67) | NR1H4FABP1HSD17B13FABP4 | |
| SCHEMBL16456713 | 0.81 | NR1H4 (0.68) | NR1H4FABP1HSD17B13FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1984360-B1 | Compounds and methods for modulating FX-receptors | LILLY CO ELI (US) | 2014-01-15 | — | — | EP | claimed |