Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977142 | 0.90 | CALCRL (0.33) | CALCRL | |
| SCHEMBL16456808 | 0.90 | CALCRL (0.36) | CALCRL | |
| SCHEMBL977158 | 0.85 | AVPR1A (0.38) | CALCRL | |
| SCHEMBL1812252 | 0.84 | CALCRL (0.38) | CALCRL | |
| SCHEMBL28717222 | 0.84 | CALCRL (0.38) | CALCRL | |
| SCHEMBL27308571 | 0.83 | CALCRL (0.35) | CALCRL | |
| SCHEMBL16495862 | 0.83 | CALCRL (0.36) | CALCRL | |
| SCHEMBL978117 | 0.83 | CALCRL (0.36) | CALCRL | |
| SCHEMBL1274952 | 0.83 | CALCRL (0.36) | CALCRL | |
| SCHEMBL979397 | 0.83 | CALCRL (0.36) | CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271346-B1 | MONOCYCLIC CGRP RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2014-01-01 | — | — | EP | disclosed |