Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 20/20 | 0.67 |
| ▸ | AKT1 | P31749 | 20/20 | 0.67 |
| ▸ | PRKCB | P05771 | 4/20 | 0.67 |
| ▸ | RPS6KA1 | Q15418 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9927836 | 1.00 | RPS6KB1 (0.67) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| SCHEMBL1662365 | 0.91 | RPS6KB1 (0.80) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| SCHEMBL1662368 | 0.91 | RPS6KB1 (0.80) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| Hydrochloric Acid SCHEMBL1662992 | 0.90 | RPS6KB1 (0.79) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| Hydrochloric Acid SCHEMBL1662990 | 0.90 | RPS6KB1 (0.79) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| SCHEMBL9894819 | 0.89 | RPS6KB1 (0.77) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| SCHEMBL9894820 | 0.89 | RPS6KB1 (0.77) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| SCHEMBL9942122 | 0.89 | RPS6KB1 (0.67) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| SCHEMBL9927829 | 0.89 | RPS6KB1 (0.72) | RPS6KB1AKT1PRKCBRPS6KA1 | |
| Hydrochloric Acid SCHEMBL16459034 | 0.88 | RPS6KB1 (0.71) | RPS6KB1AKT1PRKCBRPS6KA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491032-B1 | AKT INHIBITORS | LILLY CO ELI (US) | 2014-04-16 | — | — | EP | disclosed |