Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 20/20 | 0.75 |
| ▸ | KCNJ5 | P48544 | 17/20 | 0.53 |
| ▸ | KCNJ3 | P48549 | 17/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL12080939 | 0.99 | KCNA5 (0.74) | KCNA5KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL12081218 | 0.92 | KCNA5 (0.74) | KCNA5KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL12080970 | 0.92 | KCNA5 (0.74) | KCNA5KCNJ5KCNJ3 | |
| Hydrochloric Acid SCHEMBL12080169 | 0.91 | KCNA5 (0.61) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL1240049 | 0.91 | KCNA5 (0.81) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080448 | 0.90 | KCNA5 (0.70) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081300 | 0.90 | KCNA5 (0.70) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080500 | 0.88 | KCNA5 (0.69) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12080339 | 0.86 | KCNA5 (0.65) | KCNA5KCNJ5KCNJ3 | |
| SCHEMBL12081205 | 0.86 | KCNA5 (0.65) | KCNA5KCNJ5KCNJ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2467364-B9 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | OTSUKA PHARMA CO LTD (JP) | 2015-02-18 | — | — | EP | disclosed |
| EP-2467364-B1 | NITROGEN-CONTAINING COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF ATRIAL FIBRILLATION | OTSUKA PHARMA CO LTD (JP) | 2014-04-16 | — | — | EP | disclosed |