SCHEMBL16458677

SCHEMBL16458677

CC1=NC(C)=C(C)N(Br)C1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14907287 0.54
SCHEMBL10506619 0.54
SCHEMBL15359623 0.48
SCHEMBL25150027 0.47
SCHEMBL487087 0.42 KDM4E (0.35)
SCHEMBL25139347 0.39
SCHEMBL2379897 0.39
SCHEMBL282506 0.39
SCHEMBL369355 0.36
SCHEMBL10985269 0.36

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9321804-B2 Synthesis and use of anti-tumor drug LQC-Y 3D MEDICINES, LTD. (CN) 2016-04-26 US claimed
US-8987449-B2 Medicine for treating ischemic brain injury and its sequelae, and preparation method thereof HAIMIN LEI (CN) 2015-03-24 US claimed
US-20140011813-A1 Medicine for Treating Ischemic Brain Injury and its Sequelae, and Preparation Method Thereof HAIMIN LEI (CN) 2014-01-09 US claimed
US-20140011786-A1 SYNTHESIS AND USE OF ANTI-TUMOR DRUG LQC-Y 3D MEDICINES, LTD. (CN) 2014-01-09 US claimed
US-9321804-B2 Synthesis and use of anti-tumor drug LQC-Y 3D MEDICINES, LTD. (CN) 2016-04-26 US disclosed
US-8987449-B2 Medicine for treating ischemic brain injury and its sequelae, and preparation method thereof HAIMIN LEI (CN) 2015-03-24 US disclosed
US-20140011813-A1 Medicine for Treating Ischemic Brain Injury and its Sequelae, and Preparation Method Thereof HAIMIN LEI (CN) 2014-01-09 US disclosed
US-20140011786-A1 SYNTHESIS AND USE OF ANTI-TUMOR DRUG LQC-Y 3D MEDICINES, LTD. (CN) 2014-01-09 US disclosed