SCHEMBL16463249

SCHEMBL16463249

O=C(O)N[C@@H](Cc1ccccc1)[C@H]1COC(=O)O1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
RAB9A P51151 2/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 2/20 0.37
POLB P06746 1/20 0.37
CYP1A2 P05177 1/20 0.36
MAPK1 P28482 1/20 0.36
CAPN1 P07384 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16463252 1.00 HPGD (0.41) HPGDHTTKMT2AMEN1RAB9A
SCHEMBL17085396 0.83 ATM (0.48) HPGDHTTKMT2AMEN1LMNA
SCHEMBL5930119 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL21979446 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL2437801 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL23092514 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL495878 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL2438588 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL3508763 0.83 NPC1 (0.44) KMT2ARAB9ANPC1CYP1A2
SCHEMBL14895451 0.79 CYP1A2 (0.37) HPGDHTTKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2903974-B1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INC UNDER THE REGISTRATION OF SOCIETIES ACT AC (IN) 2016-11-23 EP claimed
EP-2903974-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES Council of Scientific & Industrial Research An Indian registered body incorporated under the Registration of Societies Act (Act XXI of 1860) (IN) 2015-08-12 EP claimed
WO-2014057500-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH AN INDIAN REGISTERED BODY INCORPORATED (IN) 2014-04-17 WO claimed
EP-2903974-B1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INC UNDER THE REGISTRATION OF SOCIETIES ACT AC (IN) 2016-11-23 EP disclosed
US-9266854-B2 One step process for synthesis of cyclic carbonates COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2016-02-23 US disclosed
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2015-09-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150259318-A1 ONE STEP PROCESS FOR SYNTHESIS OF CYCLIC CARBONATES CDY1; CDY1B, CA4, CCNY HPGD 1683/4885HTT 4737/4885KMT2A 2967/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.