Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105287 | 0.94 | MAPK14 (0.47) | MAPK14CSNK1DNR3C2CSNK1EMAPK13 | |
| SCHEMBL16105565 | 0.90 | MAPK14 (0.58) | MAPK14CSNK1DMAPK13MAPK12KCNH2 | |
| SCHEMBL16105592 | 0.90 | MAPK14 (0.46) | MAPK14CSNK1DNR3C2ABL1CSNK1E | |
| SCHEMBL16105613 | 0.89 | CSNK1D (0.58) | MAPK14CSNK1DNR3C2ABL1CSNK1E | |
| SCHEMBL16105466 | 0.89 | CSNK1D (0.46) | MAPK14CSNK1DNR3C2CSNK1EMAPK13 | |
| SCHEMBL16105288 | 0.88 | RIPK3 (0.46) | MAPK14CSNK1DNR3C2ABL1MAPT | |
| SCHEMBL1645214 | 0.88 | MAPK14 (0.51) | MAPK14CSNK1DNR3C2ABL1CSNK1E | |
| SCHEMBL16105432 | 0.87 | MAPK14 (0.42) | MAPK14CSNK1DNR3C2ABL1CSNK1E | |
| SCHEMBL16105436 | 0.87 | MAPK14 (0.43) | MAPK14CSNK1DNR3C2ABL1CSNK1E | |
| SCHEMBL16105531 | 0.87 | MAPK14 (0.45) | MAPK14CSNK1DNR3C2CSNK1EMAPK13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |