Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.37 |
| ▸ | BRAF | P15056 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647868 | 0.88 | PDE10A (0.49) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL1646701 | 0.82 | S1PR1 (0.41) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL1648437 | 0.79 | MAPK13 (0.38) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL1554947 | 0.76 | MAPK14 (0.43) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL1647136 | 0.74 | MAPK14 (0.40) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL1648133 | 0.73 | S1PR1 (0.40) | CSNK1DCSNK1EMAPK14KDRNPC1 | |
| SCHEMBL1847759 | 0.72 | BRAF (0.40) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL1645638 | 0.72 | CYP2C9 (0.45) | LMNA | |
| SCHEMBL9887881 | 0.72 | MAPK1 (0.36) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 | |
| SCHEMBL2317938 | 0.71 | BRAF (0.33) | MAPK13CSNK1DCSNK1EMAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |