⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16465661 | 1.00 | — | — | |
| SCHEMBL17615511 | 0.87 | MAPT (0.38) | — | |
| SCHEMBL28384385 | 0.81 | — | — | |
| SCHEMBL9256052 | 0.79 | — | — | |
| SCHEMBL9256049 | 0.79 | — | — | |
| SCHEMBL21610096 | 0.77 | — | — | |
| SCHEMBL20314955 | 0.77 | — | — | |
| SCHEMBL28532594 | 0.74 | MAPT (0.56) | — | |
| SCHEMBL16852848 | 0.74 | MAPT (0.56) | — | |
| SCHEMBL11033182 | 0.71 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888268-B1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INST SCIENCE & TECH SCHOOL CORP (JP) | 2018-08-22 | — | — | EP | disclosed |
| US-9309261-B2 | Spirooxindole derivative and process for producing the same | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2016-04-12 | — | — | US | disclosed |
| US-20150246927-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2015-09-03 | — | — | US | disclosed |
| EP-2888268-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | Okinawa Institute of Science and Technology School Corporation (JP) | 2015-07-01 | — | — | EP | disclosed |
| WO-2014058035-A1 | NOVEL SPIROOXINDOLE DERIVATIVE AND PROCESS FOR PRODUCING THE SAME | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2014-04-17 | — | — | WO | disclosed |