Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | HTR2C | P28335 | 2/20 | 0.59 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | HTR6 | P50406 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925919 | 0.86 | HTR2A (0.59) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL14638486 | 0.85 | SMN1; SMN2 (0.62) | HTR2AHTR2CHTR7HTR6CYP2D6 | |
| SCHEMBL11939045 | 0.84 | HTR2A (0.69) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL11297338 | 0.83 | HTR2A (0.64) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Bromide SCHEMBL11296700 | 0.83 | HTR2A (0.64) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Hydrochloric Acid SCHEMBL9232045 | 0.83 | HTR2A (0.58) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Lenperone SCHEMBL121686 | 0.83 | MEN1 (0.74) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL4981971 | 0.83 | HTR2A (0.67) | HTR2AHTR2CHTR7HTR6KDM4E | |
| Lenperone SCHEMBL11453463 | 0.82 | MEN1 (0.72) | HTR2AHTR2CHTR7HTR6KDM4E | |
| SCHEMBL10963542 | 0.81 | HTR2A (0.54) | HTR2AHTR2CHTR7HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10118892-B2 | Compounds and their synthesis | UCL BUSINESS PLC (GB) | 2018-11-06 | — | — | US | disclosed |
| US-20150266818-A1 | COMPOUNDS AND THEIR SYNTHESIS | UCL BUSINESS PLC (GB) | 2015-09-24 | — | — | US | disclosed |
| EP-2906548-A1 | COMPOUNDS AND THEIR SYNTHESIS | UCL Business Plc. (GB) | 2015-08-19 | — | — | EP | disclosed |
| WO-2014057291-A1 | COMPOUNDS AND THEIR SYNTHESIS | UCL BUSINESS PLC (GB) | 2014-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266818-A1 | COMPOUNDS AND THEIR SYNTHESIS | ARSA, CCNL2, ATXN2L | HTR2A 4107/4885HTR2C 3162/4885HTR7 3139/4885 |
| US-10118892-B2 | Compounds and their synthesis | ARSA, ATXN2L, CCNL2 | HTR2A 4065/4885HTR2C 3085/4885HTR7 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.