Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 19/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1328574 | 0.94 | GCK (0.59) | GCKCYP11B1CYP11B2 | |
| SCHEMBL1330338 | 0.91 | GCK (0.56) | GCKCYP11B1CYP11B2 | |
| SCHEMBL1328464 | 0.88 | GCK (0.62) | GCK | |
| SCHEMBL14769081 | 0.88 | GCK (0.55) | GCK | |
| SCHEMBL16467470 | 0.84 | GCK (0.63) | GCK | |
| SCHEMBL16467340 | 0.84 | GCK (0.56) | GCK | |
| SCHEMBL1329020 | 0.84 | GCK (0.70) | GCK | |
| Hydrochloric Acid SCHEMBL1329616 | 0.83 | GCK (0.69) | GCK | |
| SCHEMBL16467517 | 0.83 | GCK (0.57) | GCK | |
| SCHEMBL16467292 | 0.83 | GCK (0.56) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | claimed |