Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 15/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2655516 | 0.99 | GCK (0.52) | GCKGAALMNASLC12A5RAB9A | |
| SCHEMBL1328140 | 0.92 | GCK (0.53) | GCKGAALMNASLC12A5ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1329844 | 0.91 | GCK (0.52) | GCKGAALMNASLC12A5ALDH1A1 | |
| SCHEMBL16467303 | 0.90 | GCK (0.48) | GCKSLC12A5RAB9A | |
| SCHEMBL1328957 | 0.84 | GCK (0.70) | GCKGAARAB9AKMT2A | |
| SCHEMBL16467444 | 0.84 | GCK (0.73) | GCK | |
| Hydrochloric Acid SCHEMBL1330168 | 0.83 | GCK (0.69) | GCKGAARAB9AKMT2A | |
| SCHEMBL1327985 | 0.81 | GCK (0.47) | GCKRAB9AKMT2A | |
| SCHEMBL12247548 | 0.80 | GCK (0.59) | GCKGAARAB9AKMT2A | |
| SCHEMBL1329034 | 0.78 | GCK (0.54) | GCKGAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | claimed |