Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1330033 | 0.93 | GCK (0.47) | GCK | |
| SCHEMBL1329025 | 0.82 | GCK (0.54) | GCK | |
| SCHEMBL9072648 | 0.82 | GCK (0.49) | GCK | |
| SCHEMBL1330284 | 0.81 | GCK (0.66) | GCK | |
| SCHEMBL2339430 | 0.80 | GCK (0.49) | GCK | |
| SCHEMBL16467444 | 0.79 | GCK (0.73) | GCK | |
| SCHEMBL1328211 | 0.78 | GCK (0.59) | GCK | |
| SCHEMBL1330406 | 0.77 | GCK (0.52) | GCK | |
| SCHEMBL16467430 | 0.77 | GCK (0.70) | GCK | |
| SCHEMBL1327811 | 0.76 | GCK (0.49) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013204-B1 | 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS | ARRAY BIOPHARMA INC (US) | 2015-02-18 | — | — | EP | claimed |