SCHEMBL16467482

SCHEMBL16467482

O=C(O)N1CCCC(Cc2csc(Nc3ncc(Sc4ccnc5ccsc45)cc3Oc3ccccc3)n2)C1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCK P35557 19/20 0.49
KDR P35968 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16467437 0.92 GCK (0.51) GCK
SCHEMBL1330465 0.92 GCK (0.45) GCK
SCHEMBL1330887 0.89 GCK (0.52) GCK
SCHEMBL16466755 0.86 GCK (0.55) GCK
SCHEMBL1330573 0.85 GCK (0.47) GCK
SCHEMBL16467503 0.85 GCK (0.51) GCK
SCHEMBL1329960 0.84 GCK (0.52) GCKKDR
SCHEMBL16467538 0.84 GCK (0.48) GCK
Hydrochloric Acid SCHEMBL1329300 0.84 GCK (0.51) GCKKDR
SCHEMBL1329757 0.83 GCK (0.58) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2013204-B1 2-AMINOPYRIDINE ANALOGS AS GLUCOKINASE ACTIVATORS ARRAY BIOPHARMA INC (US) 2015-02-18 EP claimed