SCHEMBL16469719

SCHEMBL16469719

COc1ccc(/N=N/c2ccccc2O)c(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.68
KMT2A Q03164 7/20 0.68
NPC1 O15118 5/20 0.68
L3MBTL1 Q9Y468 4/20 0.68
RAB9A P51151 4/20 0.68
MAPT P10636 5/20 0.57
LMNA P02545 4/20 0.57
HTT P42858 3/20 0.57
SMN1; SMN2 Q16637 3/20 0.57
KDM4E B2RXH2 2/20 0.57
HPGD P15428 3/20 0.54
CYP1A2 P05177 3/20 0.54
PGR P06401 2/20 0.54
SLC6A2 P23975 2/20 0.54
CYP2C19 P33261 2/20 0.54
CYP3A4 P08684 2/20 0.54
ADORA3 P0DMS8 1/20 0.54
AR P10275 1/20 0.54
CHRM1 P11229 1/20 0.54
ALOX15 P16050 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16469721 1.00 MEN1 (0.68) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL28532661 0.89 MEN1 (0.57) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL25807268 0.86 MEN1 (0.73) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL23689924 0.85 MEN1 (0.62) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL21530861 0.82 MEN1 (0.66) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL21530862 0.82 MEN1 (0.66) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL9178347 0.81 NPC1 (0.54) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL9178354 0.81 NPC1 (0.54) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL17133381 0.80 NPC1 (0.56) MEN1KMT2ANPC1L3MBTL1RAB9A
SCHEMBL10899974 0.79 MEN1 (0.70) MEN1KMT2ANPC1L3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150050592-A1 TONER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT, METHOD OF MANUFACTURING THE SAME, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2015-02-19 US disclosed