SCHEMBL16470909

SCHEMBL16470909

CCOC(Cc1ccc(OCc2nc(-c3ccccc3)oc2C)cc1)C(=O)O

nearest known ligand 0.81

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PPARG P37231 18/20 0.81
PPARA Q07869 15/20 0.81
FFAR1 O14842 1/20 0.68
PPARD Q03181 3/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4028579 0.92 PPARA (0.78) PPARGPPARAFFAR1PPARD
SCHEMBL4028955 0.92 PPARA (0.78) PPARGPPARAFFAR1PPARD
SCHEMBL10211509 0.91 PPARG (0.82) PPARGPPARAPPARD
SCHEMBL4027664 0.91 PPARA (0.71) PPARGPPARAFFAR1PPARD
SCHEMBL4027656 0.91 PPARA (0.71) PPARGPPARAFFAR1PPARD
SCHEMBL4030708 0.90 PPARA (1.00) PPARGPPARAFFAR1PPARD
SCHEMBL4025374 0.89 PPARG (0.66) PPARGPPARAFFAR1PPARD
SCHEMBL4028444 0.89 PPARA (0.71) PPARGPPARAFFAR1PPARD
SCHEMBL4028440 0.89 PPARA (0.71) PPARGPPARAFFAR1PPARD
SCHEMBL4025913 0.88 PPARA (1.00) PPARGPPARAFFAR1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1250323-B1 Compounds having hypolipidemic and hypocholesterolemic activities, process for their preparation and pharmaceutical compositions containing them CADILA HEALTHCARE LTD (IN) 2014-01-01 EP disclosed