Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10155658 | 0.94 | BACE1 (0.78) | BACE1APP | |
| SCHEMBL10156446 | 0.87 | BACE1 (0.75) | BACE1APP | |
| SCHEMBL10155094 | 0.86 | BACE1 (0.80) | BACE1APP | |
| SCHEMBL10175588 | 0.85 | BACE1 (0.81) | BACE1APP | |
| SCHEMBL10154601 | 0.85 | BACE1 (0.78) | BACE1APP | |
| SCHEMBL10155374 | 0.85 | BACE1 (1.00) | BACE1APP | |
| SCHEMBL10157055 | 0.84 | BACE1 (0.84) | BACE1APP | |
| SCHEMBL4084154 | 0.84 | BACE1 (0.77) | BACE1APP | |
| SCHEMBL10154590 | 0.84 | BACE1 (0.86) | BACE1APP | |
| SCHEMBL10155165 | 0.83 | BACE1 (0.82) | BACE1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942105-B1 | AMINODIHYDROTHIAZINE DERIVATIVE | SHIONOGI & CO (JP) | 2014-04-16 | — | — | EP | disclosed |