Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2 | P60568 | 3/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3827390 | 0.94 | IL2 (0.41) | IL2METGRM5KDM4ENPC1 | |
| SCHEMBL8203992 | 0.80 | IL2 (0.41) | IL2GRM5KDM4ENPC1ALDH1A1 | |
| SCHEMBL613599 | 0.79 | IL2 (0.42) | IL2KDM4ENPC1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL616896 | 0.78 | IL2 (0.42) | IL2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL986843 | 0.77 | IL2 (0.41) | IL2KDM4ENPC1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL15653854 | 0.77 | IL2 (0.41) | IL2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL5005018 | 0.77 | IL2 (0.41) | IL2GRM5KDM4ENPC1ALDH1A1 | |
| SCHEMBL5019755 | 0.74 | IL2 (0.40) | IL2KDM4ENPC1ALDH1A1TP53 | |
| SCHEMBL16472095 | 0.74 | IL2 (0.37) | IL2GRM5KDM4ENPC1ALDH1A1 | |
| SCHEMBL3945748 | 0.74 | IL2 (0.44) | IL2KDM4ENPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086326-B1 | CYCLOHEXENYL-ARYL COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP (US) | 2014-01-08 | — | — | EP | disclosed |