Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.74 |
| ▸ | TNKS | O95271 | 8/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 3/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1549098 | 0.86 | PARP1 (0.98) | PARP1TNKSPIM1PIM2 | |
| SCHEMBL1549108 | 0.86 | PARP1 (0.72) | PARP1TNKSPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL1549634 | 0.85 | PARP1 (0.95) | PARP1TNKSPIM1PIM2 | |
| Water SCHEMBL1549890 | 0.85 | PARP1 (0.95) | PARP1TNKSPIM1PIM2 | |
| Bromide SCHEMBL1549763 | 0.85 | PARP1 (1.00) | PARP1TNKSPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL1549570 | 0.85 | PARP1 (0.71) | PARP1TNKSPIM1PIM2 | |
| SCHEMBL1549386 | 0.84 | PARP1 (0.69) | PARP1TNKSTNKS2MAPK1 | |
| Hydrochloric Acid SCHEMBL4326864 | 0.83 | PARP1 (0.68) | PARP1TNKSTNKS2MAPK1 | |
| SCHEMBL424273 | 0.82 | PARP1 (0.97) | PARP1TNKSTNKS2PIM1PIM2 | |
| Hydrochloric Acid SCHEMBL4326979 | 0.81 | PARP1 (1.00) | PARP1TNKSTNKS2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079915-B2 | Thienyl- and furanyl-isoquinolinones and methods for using them | Pellicciari, Robert (IT) | 2015-07-14 | — | — | US | disclosed |
| US-20140107117-A1 | Thienyl- and Furanyl-Isoquinolinones and Methods for Using Them | Moroni, Flavio (IT) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107117-A1 | Thienyl- and Furanyl-Isoquinolinones and Methods for Using Them | PARP1, PARP2, PARP15 | PARP1 1/4885TNKS 13/4885TNKS2 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.