Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.30 |
| ▸ | CDK2 | P24941 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
| ▸ | ATIC | P31939 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998537 | 0.75 | MYC (0.41) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL4654580 | 0.74 | TTR (0.40) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL3642842 | 0.74 | TTR (0.37) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL9797283 | 0.69 | TTR (0.36) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL306253 | 0.69 | TSHR (0.37) | TTR | |
| SCHEMBL4303162 | 0.66 | SLC7A11 (0.38) | TTRFABP4CCNA2CDK2MAPK14 | |
| SCHEMBL4303159 | 0.66 | MYC (0.34) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL13182868 | 0.65 | CA1 (0.46) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL28161246 | 0.65 | CA12 (0.52) | TTRCYP1A2MYCFABP4CCNA2 | |
| SCHEMBL2475304 | 0.64 | TTR (0.48) | TTRCYP1A2MYCFABP4CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483312-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2012-08-08 | — | — | EP | claimed |
| WO-2011039724-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI-AVENTIS (FR) | 2011-04-07 | — | — | WO | claimed |
| EP-2483312-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI (FR) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039724-A1 | ANTIBODIES THAT SPECIFICALLY BIND TO THE EPHA2 RECEPTOR | SANOFI-AVENTIS (FR) | 2011-04-07 | — | — | WO | disclosed |