Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.43 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.43 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 3/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479855 | 0.83 | LPAR1 (0.44) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL4029141 | 0.82 | LPAR1 (0.62) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL16477034 | 0.80 | LPAR1 (0.68) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL343051 | 0.79 | LPAR1 (0.56) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL343594 | 0.77 | LPAR1 (0.69) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL16477041 | 0.76 | LPAR1 (0.73) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL28398519 | 0.76 | LPAR1 (0.49) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL342658 | 0.75 | LPAR1 (0.59) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL16477186 | 0.74 | LPAR1 (0.53) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 | |
| SCHEMBL15897074 | 0.73 | LPAR1 (0.48) | LPAR1LPAR3LPAR2SMN1; SMN2ABCC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140200215-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | INTERMUNE, INC. | 2014-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140200215-A1 | LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | LPAR1, LPAR2, LPAR5 | LPAR1 1/4885LPAR3 5/4885LPAR2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.