Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949777 | 0.85 | MCHR1 (0.81) | MCHR1 | |
| Hydrochloric Acid SCHEMBL1005206 | 0.85 | MCHR1 (0.80) | MCHR1 | |
| SCHEMBL12949611 | 0.79 | MCHR1 (0.75) | MCHR1 | |
| SCHEMBL15769629 | 0.78 | MCHR1 (0.60) | MCHR1 | |
| Hydrochloric Acid SCHEMBL15768906 | 0.77 | MCHR1 (0.59) | MCHR1 | |
| SCHEMBL12927697 | 0.75 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL12927533 | 0.75 | MCHR1 (0.82) | MCHR1 | |
| Hydrochloric Acid SCHEMBL1005583 | 0.75 | MCHR1 (0.98) | MCHR1 | |
| SCHEMBL1004791 | 0.75 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL15768982 | 0.75 | MCHR1 (0.64) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448585-B1 | AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF | ALBANY MOLECULAR RES INC (US) | 2014-01-01 | — | — | EP | disclosed |