SCHEMBL16477243

SCHEMBL16477243

CCC(CC)N1CCc2c(n(C)c3nc(-n4ccc(OCc5ccccc5)cc4=O)ccc23)CC1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12927627 0.90 MCHR1 (1.00) MCHR1
SCHEMBL12927625 0.90 MCHR1 (1.00) MCHR1
Hydrochloric Acid SCHEMBL1004363 0.90 MCHR1 (0.98) MCHR1
Hydrochloric Acid SCHEMBL1004472 0.89 MCHR1 (0.98) MCHR1
SCHEMBL1004154 0.87 MCHR1 (0.84) MCHR1
SCHEMBL12927622 0.86 MCHR1 (0.81) MCHR1
SCHEMBL12927626 0.85 MCHR1 (1.00) MCHR1
Hydrochloric Acid SCHEMBL1005504 0.84 MCHR1 (0.98) MCHR1
SCHEMBL12927890 0.84 MCHR1 (1.00) MCHR1
Hydrochloric Acid SCHEMBL1004533 0.83 MCHR1 (0.98) MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2448585-B1 AZINONE-SUBSTITUTED AZEPINO[B]INDOLE AND PYRIDO-PYRROLO-AZEPINE MCH-1 ANTAGONISTS, METHODS OF MAKING, AND USE THEREOF ALBANY MOLECULAR RES INC (US) 2014-01-01 EP disclosed