Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.50 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CTSH | P09668 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478245 | 0.99 | CTSC (0.61) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478147 | 0.89 | CTSC (0.57) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478090 | 0.89 | CTSC (0.60) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478187 | 0.88 | CTSC (0.59) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478092 | 0.86 | CTSC (0.45) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478157 | 0.82 | CTSC (0.65) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478234 | 0.79 | CTSC (0.44) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478201 | 0.79 | CTSC (0.66) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478200 | 0.79 | CTSC (0.66) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL16478219 | 0.78 | CTSC (0.62) | CTSCKCNH2LTB4RLTB4R2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | claimed |
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |