Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.55 |
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16478373 | 0.84 | CTSC (0.49) | CTSCCTSKKCNH2 | |
| SCHEMBL16478330 | 0.83 | CTSC (0.60) | CTSCCTSKKCNH2USP30 | |
| SCHEMBL16485798 | 0.83 | CTSC (0.60) | CTSCCTSKKCNH2USP30 | |
| SCHEMBL16478331 | 0.81 | CTSC (0.46) | CTSCCTSKKCNH2USP30 | |
| SCHEMBL16478307 | 0.78 | CTSC (0.43) | CTSCCTSKKCNH2USP30 | |
| SCHEMBL16478308 | 0.78 | CTSC (0.43) | CTSCCTSKKCNH2USP30 | |
| SCHEMBL16478342 | 0.77 | CTSC (0.61) | CTSCCTSK | |
| SCHEMBL2072173 | 0.74 | CTSC (0.72) | CTSCCTSKKCNH2 | |
| SCHEMBL16478364 | 0.73 | CTSC (0.52) | CTSCCTSKKCNH2 | |
| SCHEMBL2072510 | 0.72 | CTSC (0.74) | CTSCCTSKKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011154677-A1 | SUBSTITUTED N-[1-CYANO-2-(PHENYL)ETHYL] 1-AMINOCYCLOALK-1-YLCARBOXAMIDE COMPOUNDS - 760 | ASTRAZENECA AB (SE) | 2011-12-15 | — | — | WO | disclosed |