⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17613598 | 0.93 | — | — | |
| SCHEMBL17613627 | 0.87 | — | — | |
| SCHEMBL12022643 | 0.87 | — | — | |
| SCHEMBL12022501 | 0.86 | — | — | |
| SCHEMBL12022654 | 0.84 | — | — | |
| SCHEMBL12022511 | 0.83 | — | — | |
| SCHEMBL13425294 | 0.83 | — | — | |
| SCHEMBL12022817 | 0.83 | — | — | |
| SCHEMBL19220451 | 0.82 | — | — | |
| SCHEMBL16480306 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346883-B1 | SELF DELIVERING BIO-LABILE PHOSPHATE PROTECTED PRO-OLIGOS FOR OLIGONUCLEOTIDE BASED THERAPEUTICS AND MEDIATING RNA INTERFERENCE | PETERSEN SCOTT G (US) | 2016-03-23 | — | — | EP | disclosed |
| US-8691971-B2 | Self delivering bio-labile phosphate protected pro-oligos for oligonucleotide based therapeutics and mediating RNA interference | KIPPERMAN, RICHARD M. | 2014-04-08 | — | — | US | disclosed |