Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 9/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13934938 | 0.84 | AR (0.62) | ARSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13934721 | 0.83 | AR (0.57) | AR | |
| SCHEMBL9891769 | 0.83 | AR (0.40) | AR | |
| SCHEMBL9892990 | 0.83 | ABL1 (0.44) | ABL1PARP1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL19745913 | 0.83 | AR (0.38) | ARPARP1 | |
| SCHEMBL19745911 | 0.83 | AR (0.38) | ARPARP1 | |
| SCHEMBL9103503 | 0.81 | NR3C2 (0.40) | ARCHRM2CHRM5CHRM1 | |
| SCHEMBL19745517 | 0.81 | HDAC1 (0.52) | ARPARP1 | |
| SCHEMBL9103496 | 0.81 | NR3C2 (0.40) | ARCHRM2CHRM5CHRM1 | |
| SCHEMBL19745519 | 0.81 | HDAC1 (0.52) | ARPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629157-B2 | Pyrrolidine compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-01-14 | — | — | US | disclosed |