Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 14/20 | 0.82 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16464915 | 0.91 | XIAP (0.82) | XIAPMMEACE | |
| SCHEMBL3722659 | 0.91 | XIAP (0.82) | XIAPMMEACE | |
| SCHEMBL17052780 | 0.90 | XIAP (1.00) | XIAPFNTAFNTB | |
| Hydrochloric Acid SCHEMBL16464346 | 0.89 | XIAP (0.98) | XIAPFNTAFNTB | |
| Hydrochloric Acid SCHEMBL16464354 | 0.89 | XIAP (0.98) | XIAPFNTAFNTB | |
| SCHEMBL20459295 | 0.86 | XIAP (0.74) | XIAP | |
| SCHEMBL16463734 | 0.84 | XIAP (1.00) | XIAPFNTAFNTBMMEACE | |
| SCHEMBL16484028 | 0.83 | XIAP (1.00) | XIAP | |
| SCHEMBL20459228 | 0.83 | XIAP (1.00) | XIAP | |
| SCHEMBL16482924 | 0.81 | XIAP (1.00) | XIAPFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014056755-A1 | INDOLINES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-04-17 | — | — | WO | disclosed |