Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.44 |
| ▸ | TDP2 | O95551 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483086 | 0.97 | NPC1 (0.54) | NPC1POLBRAB9APDGFRBPDGFRA | |
| SCHEMBL16483458 | 0.95 | PDGFRB (0.51) | NPC1POLBRAB9APDGFRBPDGFRA | |
| SCHEMBL16483536 | 0.91 | POLB (0.62) | NPC1POLBRAB9APIK3CAPIK3CD | |
| SCHEMBL16483100 | 0.91 | PDGFRB (0.54) | PDGFRBPDGFRAPIK3CAPIK3CDCYP2A6 | |
| SCHEMBL16483465 | 0.90 | ERN1 (0.48) | NPC1POLBRAB9APDGFRBPDGFRA | |
| SCHEMBL16483091 | 0.90 | NPC1 (0.51) | NPC1POLBRAB9APDGFRBPDGFRA | |
| SCHEMBL13682493 | 0.89 | POLB (0.60) | NPC1POLBRAB9APIK3CADYRK1A | |
| SCHEMBL16483650 | 0.88 | PDGFRB (0.47) | NPC1POLBRAB9APDGFRBPDGFRA | |
| SCHEMBL15497847 | 0.88 | PDGFRB (0.54) | PDGFRBPDGFRAPIK3CAPIK3CDCYP2A6 | |
| SCHEMBL16483098 | 0.87 | POLB (0.54) | NPC1POLBRAB9APIK3CADYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |