Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.62 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CDK7 | P50613 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15497847 | 0.88 | PDGFRB (0.54) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA | |
| SCHEMBL16483281 | 0.88 | CYP2A6 (0.64) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA | |
| SCHEMBL16483100 | 0.85 | PDGFRB (0.54) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA | |
| SCHEMBL15497834 | 0.85 | PDGFRB (0.51) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA | |
| SCHEMBL16483767 | 0.85 | NPC1 (0.50) | PDGFRBPDGFRAPIK3CAMAPK10MAP4K4 | |
| SCHEMBL16483278 | 0.85 | NPC1 (0.50) | PDGFRBPDGFRAPIK3CAMAPK10MAP4K4 | |
| SCHEMBL19768482 | 0.84 | PDGFRB (0.49) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA | |
| SCHEMBL16483108 | 0.84 | NPC1 (0.53) | PDGFRBPDGFRAPIK3CAMAPK10MAP4K4 | |
| SCHEMBL16483258 | 0.84 | PDGFRB (0.43) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA | |
| SCHEMBL17322716 | 0.82 | PDGFRB (0.49) | PDGFRBPDGFRACYP2A6PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |