SCHEMBL1648334

SCHEMBL1648334

CC(Cc1ccc(O)cc1)c1ccccc1C(C)Cc1ccc(O)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 5/20 0.64
ESR2 Q92731 5/20 0.64
TAAR1 Q96RJ0 3/20 0.55
SLC6A2 P23975 2/20 0.55
SIGMAR1 Q99720 1/20 0.50
TSHR P16473 2/20 0.45
SOAT2 O75908 1/20 0.44
SOAT1 P35610 1/20 0.44
ADRB2 P07550 5/20 0.42
CYP3A4 P08684 2/20 0.42
MAPK1 P28482 2/20 0.42
CYP2D6 P10635 1/20 0.42
HIF1A Q16665 1/20 0.42
HSD17B10 Q99714 1/20 0.42
ADRB1 P08588 1/20 0.42
ADORA3 P0DMS8 1/20 0.42
ADRB3 P13945 1/20 0.42
PTGS1 P23219 1/20 0.42
HTR2A P28223 1/20 0.42
SLC6A4 P31645 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7210624 0.90 TSHR (0.60) ESR1ESR2TAAR1SLC6A2SIGMAR1
SCHEMBL3047457 0.83 TSHR (0.67) ESR1ESR2TAAR1SLC6A2SIGMAR1
SCHEMBL1936402 0.82 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2SIGMAR1
SCHEMBL4602654 0.82 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2SIGMAR1
Ammonia Solution, Strong SCHEMBL8866157 0.80 ESR1 (0.78) ESR1ESR2TAAR1SLC6A2SIGMAR1
SCHEMBL28439539 0.80 ESR1 (0.60) ESR1ESR2TAAR1SLC6A2TSHR
SCHEMBL22660974 0.79 NPC1 (0.46) TAAR1SLC6A2SIGMAR1TSHRADRB2
Hydrochloric Acid SCHEMBL8865826 0.79 ESR1 (0.75) ESR1ESR2TAAR1SLC6A2SIGMAR1
Ammonia Solution, Strong SCHEMBL8976244 0.79 ESR1 (0.81) ESR1ESR2TAAR1SLC6A2SIGMAR1
SCHEMBL10439615 0.79 ESR1 (0.58) ESR1ESR2TAAR1SLC6A2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2552995-B2 MELT POLYCARBONATE HAVING IMPROVED HEAT AGEING COVESTRO DEUTSCHLAND AG (DE) 2022-01-05 EP disclosed
EP-2552995-B1 MELT POLYCARBONATE HAVING IMPROVED HEAT AGEING COVESTRO DEUTSCHLAND AG (DE) 2015-12-02 EP disclosed
CN-102276818-B Branched melt polycarbonates with low content of defective structures BAYER MATERIALSCIENCE AG 2015-01-14 CN disclosed
EP-2483340-B1 UV-STABLE POLYCARBONATE COMPOSITIONS WITH IMPROVED PROPERTIES BAYER IP GMBH (DE) 2014-12-17 EP disclosed
EP-2374830-B1 Branched melt polycarbonate with low proportion of faulty structures BAYER IP GMBH (DE) 2014-10-08 EP disclosed
US-8716380-B2 Polycarbonate composition having improved heat stability BAYER MATERIALSCIENCE AG (DE) 2014-05-06 US disclosed
EP-2308920-B1 Polycarbonate compound with improved thermal stability BAYER IP GMBH (DE) 2013-07-17 EP disclosed
US-8487025-B2 Branched melt polycarbonate with low content of defective structures BAYER MATERIAL SCIENCE AG (DE) 2013-07-16 US disclosed
EP-2305748-B1 Polycarbonate compound having improved melt flow behaviour BAYER MATERIALSCIENCE AG (DE) 2013-02-13 EP disclosed
US-20120232196-A1 UV-STABLE POLYCARBONATE COMPOSITION HAVING IMPROVED PROPERTIES BAYER MATERIALSCIENCE AG (DE) 2012-09-13 US disclosed
EP-1377625-B1 POLYCARBONATE HAVING A PRONOUNCED SHEAR THINNING BEHAVIOR BAYER MATERIALSCIENCE AG (DE) 2006-06-14 EP disclosed
US-6858303-B2 Polycarbonate containing diphenyl carbonate and sheets made therefrom BAYER AKTIENGESELLSCHAFT (DE) 2005-02-22 US disclosed
US-6770731-B2 MELT POLYMERIZED BRANCHED POLYCARBONATE WITH NON-NEWTONIAN FLOW BEHAVIOR: GOOD FLOWABILITY AT HIGH SHEAR RATES, AND IS NOT LESS FLOWABLE THAN UNBRANCHED POLYCARBONATE AT LOW SHEAR RATES BAYER AKTIENGESELLSCHAFT (DE) 2004-08-03 US disclosed
US-20040122147-A1 Polycarbonate containing diphenyl carbonate and sheets made therefrom BAYER AKTIENGESELLSCHAFT (DE) 2004-06-24 US disclosed
US-6699959-B2 EXHIBITS A FLOW BEHAVIOR SIMILAR TO THAT OF A LINEAR POLYCARBONATE OF COMPARABLE MOLECULAR WEIGHT OBTAINED BY THE INTERFACE POLYMERIZATION PROCESS. BAYER AKTIENGESELLSCHAFT (DE) 2004-03-02 US disclosed
EP-1377624-A1 POLYCARBONATE HAVING A LOW SHEAR THINNING RATIO Bayer Aktiengesellschaft (DE) 2004-01-07 EP disclosed
US-20030027973-A1 Polycarbonate having a low shear thinning behavior BAYER AKTIENGESELLSCHAFT (DE) 2003-02-06 US disclosed
US-20030013839-A1 Polycarbonate having pronounced shear thinning behavior BAYER AKTIENGESELLSCHAFT (DE) 2003-01-16 US disclosed
US-20030013788-A1 Melt polycarbonate with improved resistance to hydrolysis BAYER AKTIENGESELLSCHAF (DE) 2003-01-16 US disclosed
WO-2002077064-A1 POLYCARBONATE HAVING A LOW SHEAR THINNING RATIO BAYER AKTIENGESELLSCHAFT (DE) 2002-10-03 WO disclosed