Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 5/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 5/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.31 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483482 | 0.92 | TNF (0.38) | TNFCKS1BSKP2CYP11B1CYP11B2 | |
| SCHEMBL16483169 | 0.91 | COMT (0.35) | CKS1BSKP2COMTGLO1ENPP1 | |
| SCHEMBL16484857 | 0.90 | TNF (0.39) | TNFDYRK1ACYP11B1CYP11B2MAPK14 | |
| SCHEMBL16484912 | 0.90 | TNF (0.41) | TNFDYRK1ACYP11B1CYP11B2ENPP1 | |
| SCHEMBL16483718 | 0.90 | COMT (0.37) | CKS1BSKP2COMTGLO1ENPP1 | |
| SCHEMBL16483555 | 0.87 | TNF (0.36) | TNFCKS1BSKP2DYRK1ACYP11B1 | |
| SCHEMBL16483713 | 0.87 | COMT (0.34) | CKS1BSKP2COMTGLO1ENPP1 | |
| SCHEMBL16483583 | 0.86 | PDE4A (0.38) | CKS1BSKP2COMTGLO1ENPP1 | |
| SCHEMBL16483433 | 0.86 | TNF (0.40) | TNFDYRK1ACYP11B1CYP11B2CDK4 | |
| SCHEMBL16483724 | 0.85 | COMT (0.33) | CKS1BSKP2COMTGLO1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |