Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16483333 | 1.00 | POLB (0.49) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16484860 | 0.94 | NPC1 (0.50) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16483268 | 0.91 | POLB (0.51) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16483067 | 0.88 | POLB (0.60) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16483772 | 0.88 | POLB (0.60) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16483418 | 0.88 | POLB (0.53) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16483258 | 0.88 | PDGFRB (0.43) | DYRK1AGRM4AKR1C3AKR1C2PIK3CD | |
| SCHEMBL16483089 | 0.85 | POLB (0.60) | POLBNPC1RAB9ADYRK1AGRM4 | |
| SCHEMBL16483777 | 0.85 | DHODH (0.42) | POLBNPC1RAB9AALDH1A1TP53 | |
| SCHEMBL16483748 | 0.85 | DHODH (0.42) | POLBNPC1RAB9AALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |