Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.55 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.55 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.55 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.55 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.55 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.55 |
| ▸ | BRAF | P15056 | 7/20 | 0.47 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | FRK | P42685 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1647083 | 0.83 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1554772 | 0.80 | KMT2A (0.35) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL16105552 | 0.80 | CSNK1D (0.53) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1644870 | 0.78 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1647484 | 0.78 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL16105633 | 0.78 | MAPK14 (0.54) | MAPK14MAPK10 | |
| SCHEMBL16105403 | 0.77 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL16105636 | 0.77 | CSNK1D (0.42) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL16105554 | 0.76 | RIPK3 (0.43) | MAPK14MAPK13MAPK12MAPK11CSNK1D | |
| SCHEMBL1645969 | 0.76 | MAPK14 (0.49) | MAPK14MAPK13MAPK12MAPK11CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2784071-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784073-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784070-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2784072-A1 | 3-PHENYL-4-PYRI(MI)DINYL-1H-PYRAZOLES AND THEIR USE AS FUNGICIDES | Bayer CropScience AG (DE) | 2014-10-01 | — | — | EP | disclosed |
| EP-2308866-A1 | Phenylpyri(mi)dinylpyrazoles and their use as fungicides | Bayer CropScience AG (DE) | 2011-04-13 | — | — | EP | disclosed |