Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | GSR | P00390 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16484845 | 0.88 | RECQL (0.44) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL16484865 | 0.87 | RECQL (0.48) | RECQLESR1ESR2GSRMAPK1 | |
| SCHEMBL12232034 | 0.86 | MAPT (0.43) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL12232109 | 0.85 | AOC3 (0.45) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL16483382 | 0.84 | MEN1 (0.42) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL12232106 | 0.83 | ESR1 (0.55) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL12232104 | 0.83 | ESR1 (0.55) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL12232069 | 0.83 | ESR1 (0.55) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL12232068 | 0.83 | RECQL (0.47) | MAPTAOC3RECQLESR1ESR2 | |
| SCHEMBL16484878 | 0.82 | RECQL (0.42) | RECQLESR1ESR2GSRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014057873-A1 | PHOSPHINE OXIDE DERIVATIVE AND LIGHT-EMITTING ELEMENT PROVIDED WITH SAME | 東レ株式会社 (JP) | 2014-04-17 | — | — | WO | disclosed |