SCHEMBL1648517

SCHEMBL1648517

Cc1ccc2c(CO)cccc2c1

nearest known ligand 0.57

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.57
CYP2C19 P33261 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2C9 P11712 1/20 0.45
CYP2A6 P11509 3/20 0.44
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
NLRP3 Q96P20 1/20 0.42
F12 P00748 1/20 0.41
IDH1 O75874 2/20 0.41
CYP2D6 P10635 1/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
HPGD P15428 1/20 0.40
HSD17B10 Q99714 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23527419 0.83 CYP2C19 (0.55) CYP1A2CYP2C19CYP3A4CYP2C9CYP2A6
SCHEMBL7747919 0.82 CYP1A2 (0.59) CYP1A2CYP2A6TDP1MEN1KMT2A
Ammonia Solution, Strong SCHEMBL27919138 0.81 CYP1A2 (0.57) CYP1A2CYP2A6TDP1MEN1KMT2A
SCHEMBL15345458 0.81 CYP1A2 (0.57) CYP1A2CYP2A6TDP1MEN1KMT2A
SCHEMBL14496748 0.81 CYP1A2 (0.57) CYP1A2CYP2C19CYP3A4CYP2C9CYP2A6
SCHEMBL19799060 0.80 CYP1A2 (0.57) CYP1A2CYP2C19CYP3A4CYP2C9CYP2A6
SCHEMBL14564415 0.79 TDP1 (0.64) CYP1A2TDP1MEN1KMT2AL3MBTL1
SCHEMBL3045619 0.78 MAPK1 (0.45) CYP1A2CYP2C19CYP2C9TDP1CYP2D6
SCHEMBL30504155 0.78 MAPK1 (0.45) CYP1A2CYP2C19CYP2C9TDP1CYP2D6
SCHEMBL28902599 0.78 CYP1A2 (0.53) CYP1A2CYP2A6TDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923418-B2 Emulsion breaker BAKER HUGHES INCORPORATED (US) 2011-04-12 US disclosed
US-20090298722-A1 Emulsion Breaker BJ SERVICES COMPANY (US) 2009-12-03 US disclosed